Alesion, or chancre, or open crater about the size of a dime is indicative of

This is a sign of the primary stage of syphilis. These lesions, or chancres, will show up in the exact spot that the bacteria originally entered the body. This is generally a sign of the infection. The illness often incubates for long periods of time, from between ten and ninety days, so it could be months from the original contact.

It settles nerves, reduces the tension.

Pretty bad i would assume.