What is the name of the factor that comes before and paves the way for a later onset of the disorder? primary?

The skin includes multiples layers. which of the following is not one of the layers of the skin?

Lina went camping in the woods. while camping, she accidentally touched a strange plant. her hand immediately started itching, and her skin erupted in hives. after she got home, her grandmother cooked some oatmeal, wrapped it in a cloth, and put it on lina’s affected hand. lina’s grandmother followed a traditional remedy.

John is jogging on a winter day. the outdoor temperature is 31° f. yet his body temperature is 98°f. which term best describes the process causing this difference in temperature?