The addition, removal, or substitution of nitrogenous bases in a DNA molecule may be caused by . Synapsis C. Disjunction B. Hybridization D. Mutation

D. Mutation

Explanation:

Mutation is any change or alteration that occurs to the nucleotide sequence of a gene induced during DNA replication or by mutation-causing substances called MUTAGENS.

Mutation can be in the form of addition, removal, or substitution of nitrogenous bases in a DNA molecule. For example, in an original DNA sequence as follows: GAT ATC TGA, the following mutation can occur:

Addition: GAT ATC CTG A

Removal: GAT ATT GA

Substitution: GAT CTC TGA