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Chemistry, 02.03.2021 01:00 Hoeing3195

Design a synthesis of m-bromostyrene from benzene. 1284q Part 1: Choose the best option for the immediate precursor to the target molecule. 1284p1 1284p1b 1284p1a 1284p1e 1284p1d 1284p1c Dehydrohalogenation of the benzylic bromine can result in an alkene. Part 2: Choose the best option for the precursor needed to make the dibromide intermediate. 1284p2 1284p2d 1284p2c 1284p2b 1284p2a 1284p2e Bromination of the benzylic position of an ethyl group is easily accomplished and leads to the desired dibromide. Part 3: Choose the best option for the precursor needed to make the aryl bromide. 1284p3 1284p3a 1284p3e 1284p3d 1284p3c 1284p3b There are reductive methods which will convert a ketone carbonyl group to an methylene carbon (CH2) in one step. Part 4: Choose the best option for the precursor needed to make the keto-bromide intermediate. 1284p4 1284p4a 1284p4e 1284p4d 1284p4c 1284p4b An acetyl group is a meta director and will direct electrophilic bromination of the ring to the meta position. Part 5: Choose the best option for the precursor needed to make acetylbenzene (acetophenone). 1284p5 1284p5b 1284p5a 1284p5e 1284p5d 1284p5c Electrophilic acylation of benzene will give rise to the desired compound. Part 6 out of 12 Here is an overview of your retrosynthesis (there is no work, this is just a recap). 1284p6

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Design a synthesis of m-bromostyrene from benzene. 1284q Part 1: Choose the best option for the imme...
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