What would happen to mapk signaling if you injected the cells with a nonhydrolyzable form of gtp?

MAPK signalling

Explanation:

MAPK stands for mitogen activated protein kinase

Ras-MAPK pathway includes cell division and differentiationAll growth factors which induce cell division transfer their signal by Ras-MAPK pathwayRas-MAPK pathway starts with the binding of insulin hormone to receptor and autophosphorylation on its own tyrosine residuePhosphotyrosine residue of receptor recognized by a scaffold protein called insulin receptor substrate(IRS-1)Phosphotyrosine residue of IRS-1 recognized by a signaling protein called Grb2Grb2 binds to the phosphotyrosine of IRS-1 and provides binding site for SOS proteinSOS binds to Grb2,then to Ras and act as guanosine exchange factor causing exchange of GDP to GTP on Ras proteinRas is a monomeric protein and activated Ras binds to kinase protein and activate it through phosphorylation which further leads to initiation of cell division If cells are injected with a non-hydrolyzable form of GTP then Ras would be active all the time which will lead to uncontrolled cell division(cancer)