Mis amigos loles, antonio y karen (1) preguntan a mí si quiero ir a italia con ellos este verano.

1. me

Explanation:

The unstressed personal pronouns are those that function as a direct or indirect complement (“Te lo dije”: "te" OI "lo" OD) or as part of the pronominal verbs: “me arrepiento”.

The forms of singular “me” and “te” and those of plural “nos” and “tus” are used without distinction of gender, and the same as a direct rather than indirect complement, so it is necessary to be able to distinguish when they are one and when another, attend not only to the nature of the verb, but also, in most cases, to the context.