People experiencing hopelessness often have than optimistic people.

People experiencing a depressed hopelessness often have reduced disease-fighting immune systems than optimistic people. The people they are also some of the most frustrating feelings that depressed individuals experience. Research on the cognitive theory of depression has shown that people who are depressed struggle with feelings of hopelessness and helplessness more so than people who are not depressed. So they have reduced disease-fighting immune system.

It’s either d or b ! but it might be b