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According to ohrp, a problem is an “unanticipated problem” when it meets which of the following criteria: unexpected, related or possibly related to the research, suggests that the research does not put the subjects or others at greater riskunexpected, related or possible related to the research, suggests the research puts subjects or others at greater riskunexpected, unrelated to the research but still occurring with a subject, suggests the research puts others at greater riskexpected, related or possible related to the research, suggests the research puts others at greater risk

Imperial crisis inflation invasion pax romana great schismtrade during the , roman generals warred over succession. these conflicts drew soldiers away from the frontier and made the empire vulnerable to

Initially, northerners did not want missouri to be included in the union because 1.) maine would not be allowed to enter the union as a free state 2.) missouri wanted to enter the union as a free state 3.) missouri wanted to enter the union as a slave state 4.) maine would not be allowed to enter the union as a slave state