Acortical cell originally responded to stimulation of the middle finger. after amputation of that finger it begins responding to the second and fourth fingers. what most likely accounts for this?

Synaptic reorganization

Explanation:

A synaptic reconstruction is a form of brain plasticity indoctrinated by neuronal loss, perhaps brings about by the loss of synaptic connections of the dying neuron, a process called de-afferentation. Formation of the new germinate course includes excitation and inhibitory cells and both forms of germinating have been professed in many animal models of focal onset epilepsy and humans with incurable temporal lobe epilepsy. The brain is involved in every working including the higher cortical functions. If the affected cortical network is in the visual cortex the clinical demonstrations are visual aspect.