(a) in an experiment, cold water is poured into a bowl made of an insulating material, the container
is placed in a draught-free room. After several hours, the volume and the temperature of the
water are found to have decreased.
Name and describe the process that causes the decrease in the volume of the water, and
explain why the temperature of the water decreases.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience.b. report the adverse drug experience to the irb only if there are several other occurrences.c. report the adverse drug experience as part of the continuing review report.d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.