Which of the following factors would potentially result in a long elimination half-life of a drug?
Group of answer choices

extremely lipophilic

rapid hepatic clearance

significant renal tubular secretion

large elimination rate constant

Factors which would potentially influence the result in a long elimination half-life of a drug are

Rapid hepatic clearance

significant renal tubular secretion

Explanation:

Factors which would potentially influence the result in a long elimination half-life of a drug areRapid hepatic clearance significant renal tubular secretionHepatic drug clearance is a drug that can be defined as the volume of blood perfusing over the liver that is cleared of the drug per unit of timeintrinsic clearance is the ability of the liver to remove drug during the absence of flow in the limitations and binding to cells or proteins in the blood.Tubular secretion is also the transfer of materials from peritubular capillaries to the renal tubular lumenUrine is one of the substances leftover in the collecting duct cleared by the reabsorption and secretion.

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