Ayudaa necesito esto

Itook a better photo of the question so y’all can see it i hope it’s a fine photo

Alicense plate is to consist of 44 digits followed by 55 uppercase letters. determine the number of different license plates possible if the first and second digits must be? odd, and repetition is not permitted.

Use set builder notation to represent the following set: { -3, -2, -1, 0}