Genetic influences on cancer can be studied by manipulating the genetic makeup of mice. One of the processes that turn genes on or off (so to speak) in particular locations is called "DNA methylation." Do low levels of this process help cause tumors? Compare mice altered to have low levels with normal mice. Of 32 mice with lowered levels of DNA methylation, 22 developed tumors. None of the control group of 19 normal mice developed tumors in the same time period. Explain why we cannot safely use either the large-sample confidence interval or the test for comparing the proportions of normal and altered mice that develop tumors. One of the counts is 0. For large-sample intervals, all counts must be at least 5, and for significance testing, all counts must be at least 5. One of the counts is 0. For large-sample intervals, all counts must be at least 5, and for significance testing, all counts must be at least 10. One of the counts is 0. For large-sample intervals, all counts must be at least 10, and for significance testing, all counts must be at least 10. One of the counts is 0. For large-sample intervals, all counts must be at least 10, and for significance testing, all count