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Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.

3. meena and ala are two friends. meena has a habit of using new pens almostevery day, whereas ala believes in getting a refill for her pen instead of buyinga new pen even though her friends make fun of her.a) which out of two practices would you follow and why? b) which value is ala depicting?

Which of the following developments during the 1780s produced the strongest calls for a new national constitution and government? a.disrespect and abuse toward americans by foreign powersb.political disputes between tories and whigsc.economic chaos in the nationod.failure of states to cooperate with congress