Which presidential candidate publicly blamed hoover for great depression and beat him in election of 1932 by a significant margin?

That would be Franklin Delano Roosevelt.
In 1932, Hoover and Roosevelt were competing in the presidential elections. Hoover, a Republican, had already served as president from 1929 to 1933, and he was beaten in 1932 by Roosevelt, a Democrat. Hoover was president during the Great Depression, which Roosevelt blamed him for because of the state of America before and after it.

They had strained relationships with colonists but good relationships with american indians