How was disease to the europeans in the late 1400s and early 1500s? a.) it caused new civilizations to rise. b.) it affected people only in the americas. c.) it forced american indians to trade with europeans. d.) it weakened american indian military power.

I think the answer is D.

The right answer is "D.) It weakened American Indian military power."

Scholars believe that, among many factors, epidemic diseases were by far the largest cause of population decline among Native Americans and what helped Europeans among the colonization of the Americas. With the diminution of the indigenous population, the warriors also diminished and with that the native resistance to the colonization weakened.

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