In what context were Europeans able to take over Aztecs and Inca lands?

The two European explorers who took over the Aztec and Inca Empires were Francisco Pizzaro and Hernán Cortés. Pizzaro took over the Incas with a small army of men, winning mainly because of natural causes like chickenpox and other diseases. The Incas that didn't die, however, were thrown in line of the army. Because the Incas were a big rival of the Aztecs, they agreed to help European explorer, Hernán Cortés, conquer the Aztecs.

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the policy of appeasement influenced the beginning of ww2 because hitler gave the other countrys chocies but after they choose to try and appease hitler to not invade their country but he still invaded them.