4. What was the impact of disease on the Native American Indians?

Native Americans suffered 80-90% population losses in most of America with influenza, typhoid, measles and smallpox taking the greatest toll in devastating epidemics that were compounded by the significant loss of leadership.

zoom in on the bill of rights. the other side was just as divided: some antifederalists opposed the constitution only because it lacked a bill of rights, and others opposed it on other grounds and merely used the bill of rights as an excuse to campaign against it.