Why does the Missouri Compromise lead to the Civil War?

Missouri Compromise, (1820), in U.S. history, measure worked out between the North and the South and moved by the U.S. Congress that gave permission for the admission of Missouri as the 24th state (1821). It marked the beginning point of the length quarrel dispute sectional conflict over the extension of slavery that led to the American Civil War.

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c.) the country needed a stronger central government.