What factors led to napoleon’s defeat in russia?

There were several factors that led to Napoleon's defeat in Russia, but by far the greatest one was the harsh and long Russian winter and massive territory than broke down is army. 

Cherokee  removal, part of the trail of tears, refers to the  forced  relocation between 1836 and 1839 of thecherokee  nation from  their lands ingeorgia, south carolina, north carolina, tennessee, texas, and alabama to the indian territory (present day oklahoma)  in  the thenwestern united states, and the resultant deaths