Anti-semitism has been a cultural issue since ancient times. the rise of anti-semitism in europe prior to and during world war ii was a direct cause of which event?

   Holocaust

Explanation:  Anti-Semitism is an antagonism towards Jews based on prejudice. The reasons for this antagonism are rooted from ancient times on the basis of myths and stereotypes, and in part are practical reasons, unjustified guilt for poor economic conditions. Thus, in the Middle Ages, unseen hatred toward Jews was recorded, especially during the Crusades, when it was not rare for the Jews to experience pogrom.

Thus, on the basis of bad economic conditions at the time of the Great Depression, in Germany all the guilt were attributed to the Jews. Malicious propaganda was carried out against them, which would later lead to the Holocaust in WWII.