In the 1832 case worcester v. georgia, the us supreme court ruled
the cherokee nation should be removed to the west.
the cherokee nation could refuse to sign treaties.
individual states could impose laws on american indians.
american indians could not live east of the mississippi.

Worcester v. Georgia, was a case in which the United States Supreme CourtvacCourt vacated eviction of Samuel Worcester and held that the Georgia criminal statute that prohibited non-Native Americans from being present on Native American lands without a license from the state was unconstitutional.
So I believe the best answer would be B. the Cherokee Nation could refuse to sign treaties.