Which is not something the midwestern pioneers did when they first arrived in the midwest?

It seems that you have missed the necessary options for us to answer this question but hope this answer helps. Anyway, the things that the midwestern did when they first arrived in the midwest are the following: Rush in to claim land, started farms and built houses. Hope this helps.

Cherokee  removal, part of the trail of tears, refers to the  forced  relocation between 1836 and 1839 of thecherokee  nation from  their lands ingeorgia, south carolina, north carolina, tennessee, texas, and alabama to the indian territory (present day oklahoma)  in  the thenwestern united states, and the resultant deaths