Differing interpretations of the bible by christians in europe eventually led to
the reformation.
the hundred years’ war.
the black plague.
the italian wars.

The answer is: the Reformation.

The Reformation, which began in the 16th century, resulted in the birth of different Protestant and other forms of Christian ideologies, and it was the product of many historical events, but perhaps the most relevant ones were the different theological interpretations of the bible revolving around the notions of salvation, sin, predestination, iconography, and even the role of the Papacy.  

roosevelt, a progressive reformer, earned a reputation as a "trust buster" through his regulatory reforms and anti-trust prosecutions. his "square deal" included regulation of railroad rates and pure foods and drugs; he saw it as a fair deal for both the average citizen and the businessmen.

what exactly is the question to this?