What amendment addressed the moral issue of alcohol.

The amendment that addressed the moral issue of alcohol was the 18th Amendment.

Explanation:

The Eighteenth Amendment to the United States Constitution was ratified by Congress on January 16, 1919, banning all manufacturing, transportation (including import and export), and sale (including dispensing) of alcohol in all the nation's states and other territories. Furthermore, this constitutional amendment meant that it would come into force exactly one year after the ratification of Congress. This meant that the so-called prohibition period in the United States began on January 16, 1920. The only legal alcohol found in the United States during the prohibition period was communion wine and as a chemical product, ethanol for purposes other than consumption, for example in antiseptic contexts.

The 18th Amendment to the United States Constitution was repealed by the 21st Amendment to the Constitution on December 5, 1933, following an unexpectedly rapid process, which began with the reintroduction of beer with a maximum of 3.2% alcohol a few months earlier.