What kind of things are holding you back from doing things you want to do? 5 sentences please

What does the quote describe? “the closeness of the place, and the heat of the climate, added to the number in the ship, which was so crowded that each had scarcely room to turn himself, almost suffocated us….the shrieks of the women, and the groans of the dying, rendered the whole a scene of horror almost inconceivable.”