Anyone free to help me out? Why did the population of enslaved people increase during the period of Spanish rule in Louisiana?

The need for slave labor increased when the defeat of the Chickasaw Indians opened new land for agriculture.
The need for slave labor increased due to the invention of the cotton gin during this period.
Slaves were imported by the many American Loyalists that immigrated to Louisiana after the American Revolution.
Slave labor become more profitable in the bayous when a new vaccine for malaria was developed.