What negative impact did the Columbian exchange have on our biosphere?

Diseases were a huge negative impact. Diseases such as small pox and syphyllis were brought to the Americas by the Europeans and wiped out a large amount of the New World's population.

Explanation:

the indians crossed artificial boundaries, setting the stage for conflict

according to romans 13: 1-7, 1st peter 2: 12-14, and 1 timothy 2: 1-4, christians as citizens have specific responsibilities to a nation that gives liberties to its people. christians are obliged to live as good citizens by submitting to the human government. honor, or respect, is due to men in the high governmental station. a christian should reflect such respect not to gain some favor but because it is god’s will. peter 2: 14 notes that the purpose of the human government is to promote peace and justice in society. to submit to human government, peter includes three elements; obedience, respect, and good deeds.