In what way was the interstate commerce act most significant.

The Interstate Commerce Act created an Interstate Commerce Commission to oversee the conduct of the railroad industry. With this act, the railroads became the first industry subject to Federal regulation.

Explanation:

I believe this was the most significance the Interstate Commerce Act

enabled. :)))

you really need to put more information in your (question); /// i believe you are talking about ///creek traveler"s rest, about lewis and clark not good