Which of following occurred as a result of Constantinople's location? A It became a major center of trade.

B It was isolated from other cultures.

C It was able to control the whole empire better than Rome was.

D It was safer than Rome, so the pope moved there.

A. It became a major center of trade.

Explanation:

Constantinople's location is a major center of trade because all the goods comes from other countries into Constantinople and them go further to the western countries. They used tolls for anything passing through their rivers and waterways which ultimately enhances the economy.  Goods comes from India. Africa, China and other regions were brought into Constantinople and then shipped towards west. It also safer empire because of its geographic location which  boost the trade in this region.

d. she conquered the black sea coast and parts of poland.