When does Fred Wilson say someone does their best work?

When they have a cheerleader in their lives.

Explanation:

Fred Wilson is a Venture Capitalist. During one of his talks, he explained that people can produce their best work when they have a cheerleader in their lives. The cheerleader is the person who sees the potentials in you and believes in your dreams. The person in turn spurs you on to action, encouraging you to take the needed steps to succeed in your goals.

His own cheerleader was his wife, Gotham Gal, whom he said has always believed in him and encouraged him to succeed.

1.3x - 2 - (3.3x + 5) = 2x + 1

1.3x - 2 - 3.3x - 5 = 2x + 1

-2x - 7 = 2x + 1

-7 = 4x + 1

-8 = 4x

x = -2