Which of these was a major issue dividing the federalist and republican parties

This was because they had disagreements on how large and powerful the federal government should be.

The Federalists were in support of a strong central government system which should be run by well-educated people. The Democratic-Republicans wanted most power to stay with the states and wanted the 'common man' to run the country.

there are no mutiple choices here

the answer is b: the religion they practice.

here's why:

there were many different native american tribes and those with similar characteristics formed a main tribe or nation. each had its own language, religion and customs.