The location of the first battle of bull run was significant because

The First Battle of Bull Run or the First Battle of Manassas as it is also called, resulted in thousands of lives lost; and as such it if referred to as first major land battle of the American Civil war. It was an incident of high importance where two untried armies met on the battlefield for the first time.

Explanation:

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according to the passage the most suitable options are two. the first one is "by leading the aef to victory in several key battles" like the battle of saint- mihiel and the battle of cantigny mentioned in the passage you copied here. the second one is "by the aef and allied forces defeat germany" since the passage says that his army destroy the german resistance in the meuse- argonne offensive. and also, "by insisting that the aef operate as an independent force".

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