How did the geographic location of Harappa affect trade?
The city was isolated from trading opportunities.
The city was convenient for trading opportunities.
Flooding from monsoons created more trade routes.
Flooding from monsoons limited goods available for trade.

The geographic location of Harappa made it so that

The city was convenient for trading opportunities.

Explanation:

The city of Harappa was at the bank of the Indus and was conveniently near good terrain from where there could be paths leading to Mesopotamia and the middle east.

It is in this region that most of the trade was being conducted by the civilization so it is significant that there is the situation of the place of Harappa.

It had been at the center of the trade routes for a long time.

The city was the center of trade and commerce of the civilization.