What was the main effect of the fall of Constantinople in 1453

A. the Byzantines moved northeast and formed the Russian empire

B. overland trade routes to Asia were closed

C. European forces quickly moved to retake the city

D. centuries of wide spread persecution of Jews and Christians occurred

Washington said that the united states would be "friendly and impartial" in regard to foreign conflict. what was his reason behind this statement? a jefferson and washington had determined the u.s. was too weak to wage war. b the u.s. had a treaty with both england and france, and was thus required to remain neutral. c france asked for the united states to stay out of the war, due to trade relationships. d a special envoy from england asked for strict neutrality on behalf of the united states.