One of the major effects of the introduction and widespread usage of eli whitney’s cotton gin was that

Demand for slaves grew

Explanation:

This was one of the effects of the introduction and widespread usage of Eli Whitney's cotton gin. The main effect of the cotton gin was the fact that it greatly reduced the time needed to process cotton. Because of this, cotton became a much more profitable business, and larger plantations developed. The large plantations required a very large workforce, which led to the use of more slaves in order to address this need for labor.

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