Is codiene and hydrocodone different on a drug test thats sen off?

That would be a yes. Codiene actually is a mild opioid that will metabolize in your body to form morphine which then bonds to nervous system receptors. Hydrocodone, which is somewhat synthetic while still being an opioid doesn’t make the shift instead it’s specific products bind to receptors automatically making it much more powerful. These differences are what makes the types of medications easy to distinguish.