What are orphan drugs. how are the defined in the us?

Orphan drugs are a pharmaceutical agent that has been developed to treat a rare medical condition, called Orphan disease. In the US and EU it is easier to gain marketing approval for an orphan drug, and there may be other financial incentives, such as extended exclusivity, all intended to encourage the development of drugs which might otherwise lack a sufficient profit motive.The Orphan Drug Act (ODA) of January 1983, passed in the United States, with lobbying from the National Organization for Rare Disorders and many other organizations, is meant to encourage pharmaceutical companies to develop drugs for diseases that have a small market.

The average resting heart rate (hrrest) for a 34 year old is 73 beats per minute2. 34 year old males average heart rates of 71 bpm while females average slightly higher at 76 bpm2. the normal resting heart rate range for all adults and children 10 and over is between 60 and 100 beats per minute3. 90% of 34 year olds resting pulses fall within the range of 54 to 92 bpm. in general, an adult's resting heart rate will be lower for those in better athletic condition.

Grade point average. it's literally in the name