Jacob has adjusted to the regular use of pain killers and needs to continue using these drugs in order to feel comfortable. jacobs relationship with pain killers can best be described as

Jacobs relationship with pain killers can best be described as DEPENDENCY. Drug dependency refers to the adaptive state that one developed as a result of repeated use of a particular drug. Stopping the use of such drugs usually result in withdrawal syndrome. This is because, the neurons in the user's system have become adapted to been exposed to that particular drug and they only function correctly when the drug is used. When the drug is withdrawn, several negative physiologic symptoms occur.

The answer would be fracture.