Lupe smokes a pack of cigarettes a day. what is she at risk for developing?
1.cancer
2.diabetes
3.alzheimer's disease
4.amyotrophic lateral sclerosis (als)

Lupe smokes a pack of cigarettes a day, in that situation, he's affecting his respiratory, circulatory system & can also form tumor in respiratory tract. So, out of all options, only Cancer fits best

In short, Your Answer would be Option A

Hope this helps!