It is the condition of the body to adapt to the effects of substances to the body thus requiring an even larger amount of the substance to experience the same physiological and mental effect.

Life expectancy in the united states is (76.4 for men and 81.1 for women). life expectancy is not the same as healthy life expectancy. healthy life expectancy is the number of years a person is expected to live in this number is obtained by subtracting years spent in poor health from overall life expectancy. the world health organization (who) calculates healthy life expectancy in 194 countries. the united states ranks twenty-ninth in the world using this measurement, with an average of of healthy life expectancy. singapore ranks number one (76 years), and japan is number two (75 years).