How should your hands be positioned when doing chest compressions during CPR? Place the heel of one hand over the center of the person's chest, and place the other hand on top of the first hand. Place the fingers of one hand in the center of a person's heart, and place the other hand on top of the first. Place the heel of one hand over the person's heart on the left side of the chest, and place the other hand on top of the first. Place the fingers of one hand over the person's heart on the left side of the chest, and place the other hand on top of the first.