Greg frequently gets cold sores (caused by HSV-1). He recently noticed that his left eye had a painful lesion, and he immediately made an appointment with his doctor. Greg's eye most likely became infected with the herpes virus when he touched his mouth and shortly afterward rubbed his eye, which is transmission via

A) autoinoculation.
B) direct contact.
C) indirect contact.
D) irritation.

A) autoinoculation.

Explanation:

A cold sore is defined as the painful blisters caused by the herpes simplex virus (HSV).

When Greg touched his mouth ( having cold sore)  and shortly afterward he rubbed his eyes, the virus tranmitted from mouth to his eyes via Autoinoculation.

Autoinoculation is a self infection procedure in which infections are transmitted from one part to other parts of body due to self intervining. Autoinoculation has both benefits in medical procedures such as vaccination and non-beneficial processes such as infections.

Hence, the correct option is A." Autoinoculation".