Treatment of fungal infections is more difficult than treatment of bacterial infections because the greater metabolic similarity between the fungi and their hosts limits the ability of a drug to have a selective toxicity.

The treatment of fungal infections is more difficult than treatment of bacterial infections because the greater metabolic similarity between the fungi and their hosts limits the ability of a drug to have a selective toxicity, is a TRUE statement.

Explanation:

Fungi are eukaryotic organisms which are mostly non motile and possess a rigid cell wall. Different type of fungal species has been described and some of which are capable of causing infections in both human and other animals.

Fungal infections, also called mycotic infections, can be treated with antibiotics. These antibiotics have one or more limitations such as:

- profound side effects,

- a narrow antifungal spectrum,

- poor penetration of certain tissues and

- selection of resistant fungi.

Finding suitable fungal targets is difficult because fungi, like humans, are eukaryotes. Many of the cellular and molecular processes are similar and there is often extensive homology among the genes and proteins. Therefore the above statement is CORRECT.