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In some regions where malaria is endemic, the frequency of the sickle-cell allele is as high as 15% due to heterozygous advantage for increased resistance to malaria. if modern technology were to completely eradicate malaria but not alleviate sickle-cell disease, what would be expected to happen to the sickle-cell allele frequency in subsequent generations?
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In some regions where malaria is endemic, the frequency of the sickle-cell allele is as high as 15%...
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