Insufficient production of acetylcholine in the synapses of the brain, abnormal tangled neurons, and large deposits of beta amyloid are problems associated with. a) rabies. b) alzheimer's disease. c) epilepsy. d) parkinson's disease. e) meningitis.

B) Alzheimer's disease

Explanation:

Alzheimer's disease is a neurodegenerative disease characterized by memory loss, mood swings, disorientation and behavioral issues. There are many reasons for the disease as explained by various hypothesis:

Cholinergenic hypothesis states that decreased production of neurotransmitter acetylcholine causes Azheimer's. Hence many of the current medications target to increase acetylcholine production. Tau hypothesis states that the disease is caused by tangling of neurons. This tangling is caused by aggregation of hyperphosphorylated tau protein. Amyloid hypothesis states that excess deposits of extracellular beta amyloid protein fragments are responsible for the disease. Amyloid plaques are deposited between the neurons which leads to impaired brain functioning.

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