Amalfunction in which of the following proeins below could cause anueploidy in cancer cells? rb. mad. bcl2. myc. p53.

Option). p53.

Explanation:

Aneuploidy can be defined as a type of chromosomal mutation due to abnormality in chromosome numbers. Aneuploidy represents one of the most important features of cancer cells.

The p53 (protein 53) is a tumor-suppressor protein, which prevents tumor formation by regulating cell division of mutated cells. It induces apoptosis of mutated cells having mutated DNA.

A malfunctioned or mutated p53 promotes aneuploidy in cells by inhibiting proteins of DNA repair systems which prevent chromosomal abnormalities.

Thus, the correct answer is option). p53.

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