Bile is made of water, bile salts, and

The composition of gallbladder bile is 97% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats

answer; genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes;

diseases can be cured more rapidly as medical advancements spread from region to region. -apexxx