How did Colonization along the Mississippi River lead to the founding of the United States of America that we know today?

It was one of the world's most important commercial waterways in 1 of North America's great migration routes for both birds and fishes native Americans lived along its banks and used the river for sustenance and transportation

i am a little confused myself with what goes with the letters and what goes with the numbers but ill do my best to you

the cordillera states and grand canyon are along the southwest u.s. and northern mexican pacific.

the great plains and southwest desert are also the prairie and home to many earthquakes too .

the coastal plains have poor soil and many factories started in the south.

is this what u needed? if not i can see what i can do