What is the most likely meaning "Cook and Tupaia closed the circle" at the end of the following passage (paragraph 4)?

what are the following?

hi my name is bob.hi and bye and this this tahta jjsab jjja

lennie

is very stupid, big and strong and sweet, he loves soft things

george

is smart reosponible and watches over lennie

candy

candy is an old ranch worker who has lost one of his hands in a farm accident. he's spent the best years of his life working on someone else's ranch, only to lose his hand and have little money.

curly

is the ranch owners son he is said to have vasilene in one glove to keep that hand soft for his wife

crooks

crooks. crooks is a lively, sharp-witted, black stable-hand, who takes his name from his crooked back. like most of the characters in the story, he admits that he is extremely lonely. when lennie visits him in his room, his reaction reveals this fact.

curlys wife

is lonly and seems to flirt with most of the men on the farm she does not like her hunband much.

1. the human rights issue in the novel is equlity the men in the story are poor and curly is mean to all of them as if they are just dirt

2. the first issue comes up when lennie kills the mouse

3. when lennies love for soft things gets in the way and he kills curlys wife as shes running away.

4. the issue is resolved by the death of lennie.

5. lennie suffers because of his death he will never be able to tend the rabbits.

6. the wording in the qoutations imply what is happening in the story

7. when lennies love for soft things gets in the way and he kills curlys wife as shes running away.

8.   the issue is resolved by the death of lennie.

a)   it explains that many people died because medicines and medical practices were not effective.